There aren't any managed clinical data on the protection or efficacy of VIAGRA in sufferers with retinitis pigmentosa (a minority of these patients have genetic Conditions of retinal phosphodiesterases); if prescribed, this should be performed with warning.
Following possibly oral or intravenous administration, sildenafil is excreted as metabolites predominantly inside the feces (around eighty% of administered oral dose) and also to a lesser extent within the urine (close to 13% from the administered oral dose).
VIAGRA might cause your blood pressure level to fall abruptly to an unsafe level whether it is taken with specified other medicines. Usually do not acquire VIAGRA if you're taking any other medicines termed “nitrates.
Will not consider sildenafil Until it's been prescribed to you personally by a healthcare provider. Get it as prescribed.
The indicate steady point out quantity of distribution (Vss) for sildenafil is one zero five L, indicating distribution into the tissues. Sildenafil and its key circulating N-desmethyl metabolite are the two somewhere around ninety six% bound to plasma proteins. Protein binding is unbiased of complete drug concentrations.
Legemidlet skal ikke tas sammen med grapefrukt eller grapefruktjuice da dette kan gi angina og hjerteinfarkt. Medisinen skal heller ikke tas samtidig som andre orale eller lokale behandlinger mot erektil dysfunksjon.
Denne potenspillen er en behandling for menn som lider av erektil dysfunksjon (impotens) det vil si, manglende evne til å oppnå eller opprettholde en ereksjon som varer lenge nok for tilfredsstillende seksuell nytelse.
Much better CYP3A4 inhibitors for example ketoconazole or itraconazole may very well be anticipated to have increased consequences than observed with saquinavir. A starting dose of 25 mg of VIAGRA needs to be viewed as in patients taking erythromycin or robust CYP3A4 inhibitors (for example saquinavir, ketoconazole, itraconazole) [see DOSAGE AND ADMINISTRATION, Scientific PHARMACOLOGY].
Persons with “crowded” optic disc may also be thought of at greater risk for NAION when compared to the overall inhabitants, nevertheless, proof is insufficient to support screening of possible buyers of PDE5 inhibitors, which include VIAGRA, for this uncommon issue.
Seksuell aktivitet kan være ekstra belastende for hjertet. Dersom du har hjerteproblemer eller tror du kan ha et hjerteproblem er det viktig at du opplyser om dette i samtalen med farmasøyten i apotek.
Physicians ought to go over with sufferers the elevated chance of NAION in people who have presently experienced NAION in one eye. Physicians should also examine with sufferers the enhanced threat of NAION among the overall population in sufferers by using a “crowded” optic disc, Even though evidence is inadequate to assist screening of prospective customers of PDE5 inhibitor, such as VIAGRA, for this unusual condition [see WARNINGS AND Safety measures and ADVERSE REACTIONS].
VIAGRA consists of sildenafil, which is the same medicine located in A different drug identified as REVATIO. REVATIO is made use of to deal with a unusual condition referred to as pulmonary arterial hypertension (PAH).
The main click here sign of sildenafil is cure of erectile dysfunction (incapability to sustain a satisfactory erection to accomplish sexual intercourse). Its use is currently one of many standard treatment plans for erectile dysfunction, together with for males with diabetes mellitus.[eighteen]
Within the celebration of the erection that persists more time than 4 hrs, the affected individual need to look for fast professional medical assistance. If priapism is not handled instantly, penile tissue injury and long term lack of potency could consequence.